Certainly.
Make sure that the keyword you are targeting is in:
1. Your meta title and meta description.
2. Your <h1> and <h2> titles.
3. Your ALT images, but make sure that you use a phrase with the keyword in it and not only the keyword.
4. Include your keyword in you footer at the very end of the website. Example: Copryright (c) 2009
www.yourwebsite.com - keyword
5. Name your file or page (yourwebsite.com/file.htm) after the keyword. For instance, if you are competing for the phrase 32 LCD HDTV, your file or page should be something like
www.yourwebsite.com/32-lcd-hdtv-selection.
6. Include the keyword in your content a few times in a natural way (do not stuff your content with it). You may italize it or bold it one or two times.
7. You may include some links with the keyword in it, so instead of creating a link with the word "click here" you would create one with your "keyword".
As a general rule, make sure that the first and last word the robots see on your file or page is your targeted keyword.
This should increase your relevance and thus your position in the search engines.
Good luck.